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TB & Outbreaks Week

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Tuberculosis



Study data from Colorado State University update knowledge of tuberculosis



April 14th, 2009

Researchers detail in 'Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence,' new data in tuberculosis. "Understanding the basis of bacterial persistence in latent infections is critical for eradication of tuberculosis. Analysis of Mycobacterium tuberculosis mRNA expression in an in vitro model of non-replicating persistence indicated that the bacilli require electron transport chain components and ATP synthesis for survival," investigators in the United States report.

"Additionally, low microM concentrations of aminoalkoxydiphenylmethane derivatives inhibited both the...


Source: TB & Outbreaks Week (2009-04-14)

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