TB & Outbreaks Week
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Clinical Infectious Diseases
Reports from K.J. Kugeler and colleagues advance knowledge in clinical infectious diseases
April 21st, 2009
According to a study from the United States, "In the United States, tularemia is caused by Francisella tularensis subsps. tularensis (type A) and holarctica (type B). Molecular subtyping has further divided type A into 2 subpopulations, A1 and A2." "Significant mortality differences were previously identified between human infections caused by A1 (14%), A2 (0%) and type B (7%). To verify these findings and to further define differences among genotypes, we performed a large-scale molecular epidemiologic analysis of F. tularensis isolates from humans and animals. Pulsed-field gel electrophoresis with PmeI was performed on 302 type A and 61 type B isolates. Pulsed-field...
Source: TB & Outbreaks Week (2009-04-21)
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