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Leprosy
Research conducted at C.S. Delima and co-authors has provided new information about leprosy
April 21st, 2009
According to recent research published in the journal Fems Microbiology Letters, "A heparin-binding hemagglutinin (HBHA) expressed on the surface of Mycobacterium tuberculosis is an antigenic protein that has been implicated in bacterial adherence to epithelial cells and systemic dissemination. In this study, the potential role of the Mycobacterium leprae HBHA (ML-HBHA) homologue in leprosy was investigated." "Initially, the in vivo expression of HBHA and its association with the M. leprae cell envelope was confirmed by immunoblotting and proteomic analysis. Mycobacterium leprae recombinant HBHA (rML-HBHA) bound to a heparin-Sepharose column, and its capacity to...
Source: TB & Outbreaks Week (2009-04-21)
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