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Metabolism
Investigators at University of Florida release new data on metabolism
April 21st, 2009
According to recent research published in the Journal of the American Society of Nephrology, "Increased consumption of fructose may play an important role in the epidemic of metabolic syndrome and may presage the development of diabetes, cardiovascular disease, and chronic kidney disease. Once in the cell, fructose is phosphorylated by ketohexokinase (KHK), leading to consumption of ATP, formation of AMP, and generation of uric acid through xanthine oxidoreductase (XOR)." "This study aimed to examine the direct effects of fructose in human kidney proximal tubular cells (HK-2) and whether they are mediated by the fructose metabolism via KHK. At a similar...
Source: TB & Outbreaks Week (2009-04-21)
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