TB & Outbreaks Week
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Life Sciences
Research reports from University of Geneva provide new insights into life sciences
April 28th, 2009
"To generate efficient vaccines and cures for Mycobacterium tuberculosis, we need a far better understanding of its modes of infection, persistence, and spreading. Host cell entry and the establishment of a replication niche are well understood, but little is known about how tubercular mycobacteria exit host cells and disseminate the infection," scientists writing in the journal Science report. "Using the social amoeba Dictyostelium as a genetically tractable host for pathogenic mycobacteria, we discovered that M. tuberculosis and M. marinum, but not M. avium, are ejected from the cell through an actin-based structure, the ejectosome. This conserved nonlytic...
Source: TB & Outbreaks Week (2009-04-28)
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