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Tuberculosis
Recent findings from Tor Vergata University highlight research in tuberculosis
April 28th, 2009
According to recent research from Rome, Italy, "Sarcoidosis is a systemic granulomatosis disease of unknown origin where a number of microbes, in particular M tuberculosis and non-tuberculous mycobacteria, have been hypothesized to play a role in disease pathogenesis, possibly through bacterial antigen-driven hypersensitivity. To test this concept, we used bioinformatic tools allowing the identification of antigenic peptides in whole microbial genomes to analyze the interaction between the expressed HLA-DR gene allelic variants and the HLA-DR immunome of all pathogenic bacteria in a population of 149 sarcoidosis affected subjects and 447 controls, all HLA-typed at high resolution."...
Source: TB & Outbreaks Week (2009-04-28)
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