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HIV/AIDS
Recent findings in HIV/AIDS described by Y. Kawashima and colleagues
May 5th, 2009
According to recent research from Oxford, the United Kingdom, "The rapid and extensive spread of the human immunodeficiency virus (HIV) epidemic provides a rare opportunity to witness host-pathogen co-evolution involving humans. A focal point is the interaction between genes encoding human leukocyte antigen (HLA) and those encoding HIV proteins." "HLA molecules present fragments (epitopes) of HIV proteins on the surface of infected cells to enable immune recognition and killing by CD8(+) T cells; particular HLA molecules, such as HLA-B*57, HLA-B*27 and HLA-B*51, are more likely to mediate successful control of HIV infection(1). Mutation within these epitopes can allow...
Source: TB & Outbreaks Week (2009-05-05)
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