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Legionnaire Disease
Research on legionnaire disease published by scientists at St. Antonius Hospital
May 5th, 2009
According to recent research from Nieuwegein, Netherlands, "Polymorphisms leading to deficiency of mannose-binding lectin (MBL) are associated with predisposition to infection. However, MBL deficiency can be protective against intracellular pathogens that use MBL to enter host cells." "The role of MBL genotype and activity in infection with the intracellular pathogen Legionella pneumophila was studied in a large outbreak of legionellosis at a Dutch flower show. A total of 141 patients, 65 exposed asymptomatic exhibition staff members and 670 unexposed blood bank donors were included for the study of MBL2 genotypes and MBL-mediated complement activation. Genotypic MBL...
Source: TB & Outbreaks Week (2009-05-05)
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