TB & Outbreaks Week
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Tuberculosis
Research conducted by M. Beisiegel and co-researchers has updated our knowledge about tuberculosis
May 5th, 2009
"Tuberculosis (TB) remains a global health threat. Although it is generally accepted that TB results from intensive cross-talk between the host and the pathogen Mycobacterium tuberculosis, underlying mechanisms remain elusive," scientists writing in the Journal of Infectious Diseases report. "The first evidence of human polymorphisms related to susceptibilities to distinct M. tuberculosis lineages has been gathered. Confrontation of limited host resistance with heightened bacterial virulence forms a most hazardous combination. We investigated extreme combinations, confronting inducible nitric oxide synthase-deficient (iNOS(-/-)) and wild-type (WT) mice with 2...
Source: TB & Outbreaks Week (2009-05-05)
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