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TB & Outbreaks Week

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Leishmaniasis



New leishmaniasis study findings have been published by scientists at University of London, Imperial College



May 12th, 2009

According to a study from London, the United Kingdom, "Experimental leishmaniasis is widely used to study the effector functions of T helper cell subsets in vivo. Healing and nonhealing Leishmania major infections have been correlated with T helper 1 and T helper 2 responses, respectively."

"In the present study, we determined T cell effector functions ex vivo, without any further restimulation and compared them to those obtained following antigen-specific restimulation in vitro. Our results show that T helper cell responses are significantly less polarized when determined ex vivo as compared to those measured after restimulation in vitro. Moreover, the differences in...


Source: TB & Outbreaks Week (2009-05-12)

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