TB & Outbreaks Week
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Hemorrhagic Fever
Reports summarize hemorrhagic fever research from R. Wolfel and co-authors
May 19th, 2009
According to a study from Munich, Germany, "Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis which occurs throughout Africa, Eastern Europe, and Asia and results in an approximately 30% fatality rate. A reverse transcription-PCR assay including a competitive internal control was developed on the basis of the most up-to-date genome information." "Biotinylated amplification products were hybridized to DNA macroarrays on the surfaces of polymer supports, and hybridization events were visualized by incubation with a streptavidin-horseradish peroxidase conjugate and the formation of a visible substrate precipitate. Optimal assay conditions for the...
Source: TB & Outbreaks Week (2009-05-19)
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