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TB & Outbreaks Week

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Leishmaniasis



Research from University of Lausanne in the area of leishmaniasis published



May 19th, 2009

"The levels of regulatory T cells (Treg cells), analyzed by Foxp3 mRNA expression, were determined in lesions from patients with acute cutaneous leishmaniasis (ACL) and chronic cutaneous leishmaniasis (CCL). We demonstrated that Treg cells preferentially accumulate in lesions from ACL patients during the early phase of infection (lesion duration of less than 1 month)," scientists in Epalinges, Switzerland report.

"In addition, levels of Foxp3 mRNA transcripts were significantly higher in specimens from patients with CCL than in those from patients with ACL, suggesting a critical role of intralesional Treg cells in CCL. Intralesional Treg cells from both ACL and CCL...


Source: TB & Outbreaks Week (2009-05-19)

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