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Meningitis
Research from Umea University yields new findings on meningitis
May 19th, 2009
According to a study from Umea, Sweden, "We describe the expression and regulation of the gene sfaX(II) located near the Sfa(II) fimbrial determinant in the newborn meningitis Escherichia coli (NMEC) isolate IHE3034. sfaX(II) belongs to a gene family, the 17-kDa genes, typically located downstream (300-3000 bp) of different fimbrial operons found in E. coli isolates of uropathogenic and newborn meningitis origin. Using transcriptional sfaX(II) reporter gene fusions we found that different environmental conditions commonly affecting expression of fimbrial genes also affected sfaX(II) expression." "Analysis of the sfaXII transcripts showed that the gene is part of the...
Source: TB & Outbreaks Week (2009-05-19)
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