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Meningitis
Research from University of Copenhagen has provided new information about meningitis
May 19th, 2009
"Plectasin is the first defensin-type antimicrobial peptide isolated from a fungus and has potent activity against gram-positive bacteria. By using an experimental meningitis model, the penetration of plectasin into the cerebrospinal fluid (CSF) of infected and uninfected rabbits and the bactericidal activities in CSF of the plectasin variant NZ2114 and ceftriaxone against a penicillin-resistant Streptococcus pneumoniae strain (NZ2114 and ceftriaxone MICs, 0.25 and 0.5 mu g/ml, respectively) were studied," scientists in Herlev, Denmark report. "Pharmacokinetic analysis showed that there was a significantly higher level of CSF penetration of NZ2114 through inflamed than...
Source: TB & Outbreaks Week (2009-05-19)
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