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TB & Outbreaks Week

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Obesity



Studies from University of Tennessee yield new information about obesity



May 19th, 2009

"A dramatic rise in the incidence of obesity in the U. S. has accelerated the search for interventions that may impact this epidemic. One recently recognized target for such intervention is adipose tissue, which secretes a variety of bioactive substances including prostaglandins," scientists in the United States report.

"Prostaglandin E-2 (PGE(2)) has been shown to decrease lipolysis in adipocytes, but limited studies have explored alternative mechanisms by which PGE(2) might impact obesity, such as adipogenesis or lipogenesis. Studies conducted on Apc(Min/+) mice indicated that selective inhibition of the cyclooxygenase (COX)-2 enzyme led to significant reductions in...


Source: TB & Outbreaks Week (2009-05-19)

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