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TB & Outbreaks Week

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Leishmaniasis



Research on leishmaniasis detailed by scientists at University of Sao Paulo



May 26th, 2009

According to recent research published in the journal Parasitology Research, "The liver involvement in the human visceral leishmaniasis (VL) has been related to parasitism and activated Kupffer cells with further occasional fibrotic alterations, especially after long-term disease without treatment. However, fibrotic alterations have been reported after therapy, whose clinical finding is the persistence of hepatomegaly."

"Fibrotic involvement of the liver after therapy was never well understood, and the aim of this study was to evaluate this finding through ultrastructural and morphometric analysis. A case-control study was performed with 20 patients (15 cases and...


Source: TB & Outbreaks Week (2009-05-26)

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