Tuberculosis

Study findings from Hammersmith Hospital, Imperial College provide new insights into tuberculosis

Published in TB and Outbreaks Week, May 26th, 2009

According to a study from London, the United Kingdom, "Tuberculosis (TB) pleural disease is complicated by extensive tissue destruction. Matrix metalloproteinase (MMP)-1 and -9 are implicated in immunopathology of pulmonary and central nervous system TB."

"There are few data on MMP activity in TB pleurisy. The present study investigated MMP-1, -2 and -9 and their specific inhibitors (tissue inhibitor of metalloproteinase (TIMP)-1 and -2) in tuberculous effusions, and correlated these with clinical and histopathological features. Clinical data, routine blood tests, and pleural fluid/biopsy material were obtained from 89 patients presenting with pleural effusions in a...

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Source: TB and Outbreaks Week (2009-05-26)

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