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Tuberculosis
Researchers from Case Western Reserve University detail findings in tuberculosis
June 2nd, 2009
According to recent research published in the American Journal of Respiratory Cell and Molecular Biology, "H37Rv and H37Ra have been widely used as models of virulent and avirulent strains, respectively, of Mycobacterium tuberculosis. Since the sequencing of H37Rv, microarrays have been used to investigate gene expression of M. tuberculosis strains under various conditions, and to compare gene expression of specific isolates of the organism." "Because differences in the virulence of these organisms could also be manifest via their differential induction of host genes, we used Affymetrix Human Genome Arrays U133A and U133B to evaluate human alveolar macrophage...
Source: TB & Outbreaks Week (2009-06-02)
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