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Leishmaniasis



Researchers from Federal University provide details of new studies and findings in the area of leishmaniasis



June 9th, 2009

According to recent research from Brazil, "Leishmaniasis is a parasitic disease that threatens 350 million people worldwide. In a search for new anti leishmanial drugs, the in vitro activity of flavonoids from Kalanchoe pinnata (Crassulaceae) was previously demonstrated in infected cells."

"In order to demonstrate the safety and oral activity of K. pinnata, flavonoids were evaluated in vivo in a murine model of cutaneous leishmaniasis. Daily oral doses of quercetin 3-O-alpha-L-arabinopyranosyl (1 -> 2)-alpha-L-rhamnopyranoside, quercetin 3-O-alpha-L-rhamnopyranoside, and free quercetin (16 mg/kg body weight) all were able to control the lesion growth caused by...


Source: TB & Outbreaks Week (2009-06-09)

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