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TB & Outbreaks Week

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Plague



Data on plague discussed by J.L. Zhang and colleagues



June 9th, 2009

"Coptis chinensis Franch. is a natural herb widely used in China for prevention and treatment of infectious diseases. Plague is a deadly disease caused by Yersinia pestis. Coptis chinensis Franch. is considered the therapeutic agent of choice against plague rather than conventional antibiotics because of its low cost and low toxicity," researchers in Chongqing, People's Republic of China report.

"Berberine is the major constituent of a Coptis chinensis Franch. extract. In the present study, DNA microarray was used to investigate the transcription of Y. pestis in response to berberine. The minimal inhibition concentration (MIC) of berberine to Y. pestis was determined...


Source: TB & Outbreaks Week (2009-06-09)

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