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Cholera

Data on cholera described by R.I. Joh et al

Published in TB and Outbreaks Week, June 9th, 2009

According to recent research published in the journal Bulletin of Mathematical Biology, "There are numerous examples of human pathogens which persist in environmental reservoirs while infectious outbreaks remain rare. In this manuscript, we consider the dynamics of infectious diseases for which the primary mode of transmission is indirect and mediated by contact with a contaminated reservoir."

"We evaluate the realistic scenario in which the number of ingested pathogens must be above a critical threshold to cause infection in susceptible individuals. This minimal infectious dose is a consequence of the clearance effect of the innate immune system. Infected...

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