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TB & Outbreaks Week

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Leishmaniasis



Research from D.H. Kim and co-authors yields new data on leishmaniasis



June 16th, 2009

"High cost, poor compliance, and systemic toxicity have limited the use of pentavalent antimony compounds (SbV), the treatment of choice for cutaneous leishmaniasis (CL). Paromomycin (PR) has been developed as an alternative to SbV, but existing data are conflicting," scientists in the United States report.

"We searched PubMed, Scopus, and Cochrane Central Register of Controlled Trials, without language restriction, through August 2007, to identify randomized controlled trials that compared the efficacy or safety between PR and placebo or SbV. Primary outcome was clinical cure, defined as complete healing, disappearance, or reepithelialization of all lesions. Data were...


Source: TB & Outbreaks Week (2009-06-16)

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