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Pandemics



Findings from H.M. Weingartl and co-researchers advance knowledge in pandemics



June 16th, 2009

"Swine influenza was first recognized as a disease entity during the 1918 ''Spanish flu'' pandemic. The aim of this work was to determine the virulence of a plasmid-derived human 1918 pandemic H1N1 influenza virus (reconstructed 1918, or 1918/rec, virus) in swine using a plasmid-derived A/swine/Iowa/15/1930 H1N1 virus (1930/rec virus), representing the first isolated influenza virus, as a reference," researchers in Winnipeg, Canada report.

"Four-week-old piglets were inoculated intratracheally with either the 1930/rec or the 1918/rec virus or intranasally with the 1918/rec virus. A transient increase in temperature and mild respiratory signs developed postinoculation in...


Source: TB & Outbreaks Week (2009-06-16)

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