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TB & Outbreaks Week

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Bird Flu



Researchers from Mahidol University, Medical Department publish new studies and findings in the area of bird flu



June 23rd, 2009

According to a study from Bangkok, Thailand, "Codon volatility is a method recently developed to estimate selective pressures on proteins on the basis of their synonymous codon usage. Volatility of a codon was defined as the fraction of single nucleotide substitutions that would be nonsynonymous."

"Higher volatility may indicate that the gene has been under more positive selection in the recent past. We analyzed volatility of hemagglutinin genes of H5N1 viruses in the recent outbreaks and observed differences in the volatility among viruses of different clades. The codon volatility of subclade 2.1 viruses from Indonesia was the lowest among all H5N1 clades and...


Source: TB & Outbreaks Week (2009-06-23)

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