TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Aspergillosis
Report summarizes aspergillosis study findings from Charite University
June 23rd, 2009
"Cerebral aspergillosis is increasingly recognized in severely immunocompromised patients and, until recently, this type of fungal infection was associated with a mortality approaching 100%. The central nervous system is a protected environment and penetration of drugs across the blood-brain barrier is mainly limited by their molecular size and physicochemical properties, as well as drug interaction with transporter systems (e.g., P-glycoprotein) at the blood-brain barrier," scientists writing in the journal Medical Mycology report. "Most antifungal agents are large molecules (700 Da), which makes sufficient penetration into the central nervous system unlikely....
Source: TB & Outbreaks Week (2009-06-23)
|
