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Immunotherapy

Data on immunotherapy discussed by J. Shojaeian and colleagues

Published in TB and Outbreaks Week, June 30th, 2009

"To develop an efficient dendritic cell (DC)-based immunotherapy protocol, we examined whether simultaneous pulsing of DCs with a given antigen and a third-party antigen could enhance their antigen presentation capacity. Purified splenic DCs of Balb/c mice were pulsed separately with immunoglobulin G, ovalbumin, conalbumin, P15 peptide of Mycobacterium tuberculosis, and prostate-specific antigen or double combinations of the aforementioned antigens," scientists writing in the Journal of Immunotherapy report.

"In some settings, DCs pulsed with I antigen were mixed equally with those pulsed with another antigen. Antigen-pulsed DCs were injected into the footpad of...

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