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Kidneys
Studies in the area of kidneys reported from Yeungnam University, Medical Department
June 30th, 2009
According to recent research published in the journal Acta Virologica, "Hemorrhagic fever with renal syndrome (HFRS) caused by Hantaan Virus (HTNV) is characterized by vascular hemorrhage and acute renal failure. Angiopoictin-1 (Ang-1) is a glycoprotein that maintains vessel integrity and reduces endothelial permeability." "We found that in HTNV-infected human umbilical vein endothelial cells (HUVECs) the levels of Ang-1 inRNA and protein were reduced on days 2 and 3 post-infection (p.i.), when endothelial permeability was increased. The HTNV-stimulated permeability was reduced by treatment of HUVECs with Ang-1. The plasma Ang-1 level was lower in HFRS patients...
Source: TB & Outbreaks Week (2009-06-30)
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