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Tuberculosis
Studies from N. Singh and co-researchers yield new data on tuberculosis
July 7th, 2009
"Polymorphisms of the N-acetyltransferase 2 gene (NAT2) vary remarkably between populations of different ethnic origin. The NAT2 gene determines the individual's acetylator status to metabolize drugs and xenobiotics, influencing their toxicity and efficacy profiles," scientists in Bombay, India report. "This study investigates the frequencies of the most commonly Studied NAT2 polymorphisms in a southwestern Indian population and compares these with those reported in other Indian and world populations. The association of these polymorphisms with plasma Isoniazid concentrations in a Cohort of tuberculosis patients has also been investigated. NAT2 genotyping of 201...
Source: TB & Outbreaks Week (2009-07-07)
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