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Researchers from University of Leicester publish findings in vaccines

Published in TB and Outbreaks Week, July 21st, 2009

According to recent research from Leicester, the United Kingdom, "Proactive priming before the next pandemic could induce immune memory responses to novel influenza antigens. In an open-label study, we analyzed B cell memory and antibody responses of 54 adults who received 2 7.5-mu g doses of MF59-adjuvanted A/Vietnam/1194/2004 clade 1 (H5N1) vaccine."

"Twenty-four subjects had been previously primed with MF59-adjuvanted or plain clade 0-like A/duck/Singapore/1997 (H5N3) vaccine during 1999-2001. The prevaccination frequency of circulating memory B cells reactive to A/Vietnam/1194/2004 was low in both primed and unprimed individuals. However, at day 21 after boosting,...

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