Aspergillosis
New aspergillosis findings from National Cancer Institute published
Published in TB and Outbreaks Week, July 21st, 2009
"We studied the antifungal activity of anidulafungin (AFG) in combination with voriconazole (VRC) against experimental invasive pulmonary aspergillosis (IPA) in persistently neutropenic rabbits and further explored the in vitro and in vivo correlations by using Bliss independence drug interaction analysis. Treatment groups consisted of those receiving AFG at 5 (AFG5 group) and 10 (AFG10 group) mg/kg of body weight/day, VRC at 10 mg/kg every 8 h (VRC group), AFG5 plus VRC (AFG5+VRC group), and AFG10 plus VRC (AFG10+VRC group) and untreated controls," scientists in the United States report.
"Survival throughout the study was 60% for the AFG5+VRC group, 50% for the VRC...
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