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Campylobacter

Studies from I.C. Schoenhofen et al have provided new data on campylobacter

Published in TB and Outbreaks Week, August 4th, 2009

According to recent research from Ottawa, Canada, "The sialic acid-like sugar 5,7-diacetamido-3,5,7,9-tetradeoxy-d-glycero-d-galacto-nonulosonic acid, or legion- aminic acid, is found as a virulence-associated cell-surface glycoconjugate in the Gram-negative bacteria Legionella pneumophila and Campylobacter coli. L. pneumophila serogroup 1 strains, causative agents of Legionnaire's disease, contain an alpha 2,4-linked homopolymer of legionaminic acid within their lipopolysaccharide O-chains, whereas the gastrointestinal pathogen C. coli modifies its flagellin with this monosaccharide via O-linkage."

"In this work, we have purified and biochemically characterized 11...

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