Herpesvirus
Research from Toyama University provide new insights into herpesvirus
Published in TB and Outbreaks Week, September 8th, 2009
"Chikusetsusaponin IVa and calenduloside E were isolated from the whole plant of Alternanthera philoxeroides (Mart.) Griseb (Amaranthaceae) and evaluated for their antiviral activities. Chikusetsusaponin IVa showed antiviral activities against HSV-1, HSV-2, human cytomegalovirus, measles virus, and MUMPS Virus with selectivity indices (CC50/IC50) of 29, 30, 73, 25, and 25, respectively," researchers in Toyama, Japan report.
"On the other hand, calenduloside E showed no antiviral effects against any of the viruses tested. The mode of HSV-2 action of chikusetsusaponin IVa was determined under different experimental conditions. The anti-HSV-2 target of the Compound might...
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