US Army Medical Research Institute of Infectious Diseases
Single host gene may hold key to treating both ebola and anthrax infections
Published in TB and Outbreaks Week, September 8th, 2009
Research published by Army scientists indicates that a minor reduction in levels of one particular gene, known as CD45, can provide protection against two divergent microbes: the virus that causes Ebola hemorrhagic fever and the bacterium that causes anthrax. Taken together, the results suggest a common host restriction factor and a promising approach to drug development for treating two completely different infections.
Writing in the August 20 online issue of Cell Host and Microbe, scientists at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) reported that mice expressing reduced levels of CD45 (between 11 and 77 percent) were protected...
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