Tuberculosis Cell Biology
Research from Medical University of Vienna, Institute of Physiology yields new findings on tuberculosis cell biology
Published in TB and Outbreaks Week, October 13th, 2009
Research findings, 'The essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2,' are discussed in a new report. "Mycobacterium tuberculosis represents a severe threat to human health worldwide. Therefore, it is important to expand our knowledge of vital mycobacterial processes, such as that effected by fatty acid synthase type 2 (FASII), as well as to uncover novel ones," researchers in Vienna, Austria report.
"Mycobacterial FASII undertakes mycolic acid biosynthesis, which relies on a set of essential enzymes, including 3-oxoacyl-AcpM reductase FabG1/Rv1483....
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