Meningitis

Researchers' work from University of Oxford, Medical Department focuses on meningitis

Published in TB and Outbreaks Week, October 20th, 2009

According to recent research published in the Journal of Clinical Immunology, "Complement component C8 is one of the five terminal complement components required for the formation of the membrane attack complex. Complete absence of C8 results in increased susceptibility to gram-negative bacteria such as Neisseria species."

"Two functionally distinct C8 deficiency states have been described: C8 alpha-gamma deficiency has been predominantly reported amongst Afro-Caribbeans, Hispanics, and Japanese and C8 beta mainly in Caucasians. We report a case of functional and immunochemical deficiency of the complement component C8, diagnosed in a Caucasian adult following...

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Source: TB and Outbreaks Week (2009-10-20)

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