HIV/AIDS Co-Infection

New research on HIV/AIDS co-infection from University of Florida summarized

Published in TB and Outbreaks Week, November 24th, 2009

According to recent research published in the journal Clinical Infectious Diseases, "Human immunodeficiency virus (HIV)-associated tuberculosis is difficult to treat, given the propensity for drug interactions between the rifamycins and the antiretroviral drugs. We examined the pharmacokinetics of rifabutin before and after the addition of lopinavir-ritonavir."

"We analyzed 10 patients with HIV infection and active tuberculosis in a state tuberculosis hospital. Plasma was collected for measurement of rifabutin, the microbiologically active 25-desacetyl-rifabutin, and lopinavir by validated high-performance liquid chromatography assays. Samples were collected 2-4...

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Source: TB and Outbreaks Week (2009-11-24)

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