Immunization
Studies from SIGA Technologies, Inc. yield new data on immunization
Published in TB and Outbreaks Week, February 2nd, 2010
A new study, 'Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice,' is now available. "The threat of smallpox as a bioweapon and the emerging threat of human monkeypox, among other poxviral diseases, highlight the need for effective poxvirus countermeasures. ST-246, which targets the F13L protein in vaccinia virus and its homologs in other orthopoxvirus species, provides full protection from lethal poxviral disease in numerous animal models and seems to be safe in humans," scientists in the United States report.
"All previous evaluations of ST-246 efficacy have been in immunocompetent animals. However, the risk of severe poxviral disease is...
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