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Tuberculosis

Research from K. Kazarian and co-researchers provides new data on tuberculosis

Published in TB and Outbreaks Week, February 2nd, 2010

Investigators publish new data in the report 'Expression, purification and characterization of UvrD2 helicase from Mycobacterium tuberculosis.' "Helicases appear to be important for genome stability of dormant Mycobacterium tuberculosis responsible for latent tuberculosis infection and big proportion of active disease cases caused by reactivation," scientists in Novara, Italy report.

"It was demonstrated that in both M. tuberculosis and Mycobacterium smegmatis, a helicase termed UvrD2 is essential for bacterial growth making it a promising target to fight tuberculosis. In many cases expression of soluble and active mycobacterial proteins in...

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