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Dartmouth College

New vaccine effective in preventing TB in African patients with HIV infection

Published in TB and Outbreaks Week, February 16th, 2010

Investigators from Dartmouth Medical School (DMS) have reported results of a clinical trial showing that a new vaccine against tuberculosis, Mycobacterium vaccae (MV), is effective in preventing tuberculosis in people with HIV infection. The DarDar Health Study, named for Dartmouth and Dar es Salaam, Tanzania, found that MV immunization reduced the rate of definite tuberculosis by 39 percent among 2,000 HIV-infected patients in Tanzania.

The study appears in the January 29, 2010 online issue of the journal AIDS, and it will be published in the March print issue of AIDS.

"Since development of a new vaccine against tuberculosis is a major international...

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