Tuberculosis
Research from International Center for Genetic Engineering and Biotechnology in the area of tuberculosis published
Published in TB and Outbreaks Week, April 13th, 2010
Data detailed in 'genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis' have been presented. "We performed a genome-wide siRNA screen to identify host factors that regulated pathogen load in human macrophages infected with a virulent strain of Mycobacterium tuberculosis. Iterative rounds of confirmation, followed by validation, identified 275 such molecules that were all found to functionally associate with each other through a dense network of interactions," scientists writing in the journal Cell report.
"This network then yielded to a molecular description of the host cell functional modules that...
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