Researchers detail in 'PE_PGRS antigens of Mycobacterium tuberculosis induce maturation and activation of human dendritic cells,' new data in tuberculosis. "Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis, infects one-third of the world's population. Activation of host immune responses for containment of mycobacterial infections involves participation of innate immune cells, such as dendritic cells (DCs)," researchers in Bangalore, India report.
"DCs are sentinels of the immune system and are important for eliciting both primary and secondary immune responses to pathogens. In this context, to understand the molecular pathogenesis of...
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