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Antimicrobials

Data on antimicrobials described by M. Paul et al

Published in TB and Outbreaks Week, May 25th, 2010

"Colistin has re-entered clinical use by necessity. We aimed to assess its effectiveness and safety compared with newer antibiotics," scientists in Israel report.

"This was a single-centre, prospective cohort study. Inclusion criteria were microbiologically documented pneumonia, urinary tract infection, surgical site infection, meningitis or bacteraemia treated appropriately with colistin versus imipenem, meropenem or ampicillin/sulbactam (comparators). All consecutive patients were included, only once, between May 2006 and July 2009. The primary outcome was 30 day mortality. Multivariable and Cox regression survival analyses were used to adjust comparisons between...

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