Influenza Vaccines
Data on influenza vaccines published by D. Onions and colleagues
Published in TB and Outbreaks Week, November 23rd, 2010
"Cell culture-based production methods may assist in meeting increasing demand for seasonal influenza vaccines and developing production flexibility required for addressing influenza pandemics. MDCK-33016PF cells are used in propagation of a cell-based seasonal influenza vaccine (Optaflu ®): but, like most continuous cell lines, can grow in immunocompromised mice to produce tumors," scientists writing in the journal Biologicals report.
"It is, therefore, essential that no residual cells remain within the vaccine, that cell lysates or DNA are not oncogenic, and that the cell substrate does not contain oncogenic viruses or oncogenic DNA. Multiple, redundant...
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