Dengue Fever
Chang Gung Memorial Hospital Publishes Research in Dengue Fever
Published in TB and Outbreaks Week, April 19th, 2011
2011 APR 19 -- "The C-type lectin DC-SIGN (CD209) is known to be the major dengue receptor on human dendritic cells, and a single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) is susceptible to many infectious diseases. We reason that variations in the DC-SIGN gene might have a broad influence on viral replication and host immune responses," researchers in Kaohsiung, Taiwan report.
"and Findings: We studied whether the rs4804803 SNP was associated with a susceptibility to dengue fever (DF) and/or dengue hemorrhagic fever (DHF) through genotyping analysis in a Taiwanese cohort. We generated monocyte-derived dendritic...
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