Meningitis

Investigators at University of Medicine and Dentistry of New Jersey Zero in on Meningitis

Published in TB and Outbreaks Week, May 31st, 2011

2011 MAY 31 -- "Cryptococcus neoformans is an AIDS-associated human fungal pathogen and the most common cause of fungal meningitis, with a mortality rate over 40% in AIDS patients. Significant advances have been achieved in understanding its disease mechanisms," scientists in Newark, United States report.

"Yet the underlying mechanism of a high frequency of cryptococcal meningitis remains unclear. The existence of high inositol concentrations in brain and our earlier discovery of a large inositol transporter (ITR) gene family in C. neoformans led us to investigate the potential role of inositol in Cryptococcus-host interactions. In this study, we focus on...

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Source: TB and Outbreaks Week (2011-05-31)

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