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Avian Influenza (Bird Flu)

Findings from B. Keiner and Co-Researchers Advance Knowledge in Avian Influenza (Bird Flu)

Published in TB and Outbreaks Week, September 6th, 2011

2011 SEP 6 -- A new study, "Intracellular distribution of NS1 correlates with the infectivity and interferon antagonism of an avian influenza virus (H7N1)," is now available. "Highly pathogenic avian influenza viruses of subtype H7N1 that emerged during an outbreak in 1999 and 2000 in Italy differ from their low-pathogenicity precursor viruses by changes in several genes, including three mutations in the NS1 protein. Two of them involve amino acid exchanges located within or closely adjacent to the nuclear export signal of NS1," scientists writing in the Journal of Virology report.

"The third mutation resulted in a new stop codon and thereby a...

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