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Meningitis

Findings from All India Institute of Medical Sciences Advance Knowledge in Meningitis

Published in TB and Outbreaks Week, November 1st, 2011

2011 NOV 1 -- According to the authors of a study from New Delhi, India, "Tuberculous meningitis (TBM) is a serious complication of tuberculosis that affects the central nervous system. Present methods to diagnose TBM are not suitable for early diagnosis."

"Molecular markers and sensitive methods to identify them in the early stage of infection of TBM are critically needed for efficient management. We have done the proteomic analysis of TBM cerebrospinal fluid (n=20) with 2-dimensional difference gel electrophoresis (2D-DIGE) and mass spectrometry. We identified 11 human proteins and 8 mycobacterial proteins with changed expression levels in comparison to...

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