2011 NOV 15 -- According to the authors of recent research published in the Journal of Infectious Diseases, "Guinea pigs administered an adenovirus-based Ebola virusvaccine either intramuscularly or intranasally in the presence of systemically or mucosally induced adenovirusimmunity were challenged with a lethal dose of guinea pig-adapted Zaire ebolavirus (Mayinga 1976) (GA-ZEBOV). The humoral immune response was assayed to determine the effect of vaccine delivery route and preexisting immunity."
"Intramuscular or intranasal vaccination fully protected guinea pigs against a lethal GA-ZEBOV challenge. However, intramuscular vaccination in animals...
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