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Hepatitis

Findings from BIOQUAL, Inc. Provide New Insights into Hepatitis

Published in TB and Outbreaks Week, January 17th, 2012

2012 JAN 17 -- "The role of rats in human hepatitis E virus (HEV) infections remains controversial. A genetically distinct HEV was recently isolated from rats in Germany, and its genome was sequenced," researchers in Rockville, Maryland report.

"We have isolated a genetically similar HEV from urban rats in Los Angeles, California, USA, and characterized its ability to infect laboratory rats and nonhuman primates. Two strains of HEV were isolated from serum samples of 134 wild rats that had a seroprevalence of antibodies against HEV of approximate to 80%. Virus was transmissible to seronegative Sprague-Dawley rats, but transmission was spotty and magnitude...

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