Tuberculosis
Investigators at Cornell University Release New Data on Tuberculosis
Published in TB and Outbreaks Week, January 24th, 2012
2012 JAN 24 -- New research, "Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice," is the subject of a report. According to the authors of a study from New York City, New York, "The gene Rv2136c is annotated to encode the Mycobacterium tuberculosis (Mtb) homolog of Escherichia coli's undecaprenyl pyrophosphate phosphatase. In previous work, a genetic screen of 10,100 Mtb transposon mutants identified Rv2136c as being involved in acid resistance in Mtb."
"The Rv2136c:Tn strain was also sensitive to sodium dodecyl sulfate, lipophilic antibiotics, elevated temperature and reactive oxygen and nitrogen...
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